Transfected Stable Cell Lines
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Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDFR010924
| Cat. No. | CDFR010924 |
| Description | NativeORF clone of Rattus norvegicus sodium channel, voltage-gated, type 5, alpha subunit (Scn5a) as transfection-ready DNA NM_013125.2 |
| Product Type | cDAN Clone |
| Gene Abbr | Scn5a |
| Species | Rat |
| Vector | pCMV6Entry |
| Target Gene | SCN5A |
| Background | The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene have been associated with long QT syndrome type 3 (LQT3), atrial fibrillation, cardiomyopathy, and Brugada syndrome 1, all autosomal dominant cardiac diseases. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, May 2022] |
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