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shRNA set against Human SCN5A (NM_000335.4)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH402880

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Gene Information

Cat. No. SHH402880
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr SCN5A
Gene Name SCN5A sodium channel, voltage-gated, type V, alpha subunit [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name SCN5A sodium channel, voltage-gated, type V, alpha subunit [ Homo sapiens ]
Gene Symbol SCN5A
Synonyms HB1; HB2; HH1; IVF; VF1; HBBD; ICCD; LQT3; SSS1; CDCD2; CMD1E; CMPD2; PFHB1; Nav1.5
Gene Description sodium channel, voltage-gated, type V, alpha subunit
GeneID 6331
Uni ProtID Q14524
mRNA Refseq NM_000335.4
Protein Refseq NP_000326.2
Chromosome Location 3p21
Function ankyrin binding; calmodulin binding; ion channel binding; protein binding; scaffold protein binding; voltage-gated sodium channel activity; voltage-gated sodium channel activity involved in regulation of cardiac muscle cell action potential; voltage-gated sodium channel activity involved in regulation of cardiac muscle cell action potential;
Pathway Axon guidance, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Interaction between L1 and Ankyrins, organism-specific biosystem; L1CAM interactions, organism-specific biosystem; SIDS Susceptibility Pathways, organism-specific biosystem;
MIM 600163
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