Transfected Stable Cell Lines
Reliable | High-Performance | Wide Rage
Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : SHH402880
| Cat. No. | SHH402880 |
| Description | The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells. |
| Gene Abbr | SCN5A |
| Gene Name | SCN5A sodium channel, voltage-gated, type V, alpha subunit [ Homo sapiens ] |
| Species | Human |
| Report Gene | GFP |
| Storage | The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C. |
| Gene Name | SCN5A sodium channel, voltage-gated, type V, alpha subunit [ Homo sapiens ] |
| Gene Symbol | SCN5A |
| Synonyms | HB1; HB2; HH1; IVF; VF1; HBBD; ICCD; LQT3; SSS1; CDCD2; CMD1E; CMPD2; PFHB1; Nav1.5 |
| Gene Description | sodium channel, voltage-gated, type V, alpha subunit |
| GeneID | 6331 |
| Uni ProtID | Q14524 |
| mRNA Refseq | NM_000335.4 |
| Protein Refseq | NP_000326.2 |
| Chromosome Location | 3p21 |
| Function | ankyrin binding; calmodulin binding; ion channel binding; protein binding; scaffold protein binding; voltage-gated sodium channel activity; voltage-gated sodium channel activity involved in regulation of cardiac muscle cell action potential; voltage-gated sodium channel activity involved in regulation of cardiac muscle cell action potential; |
| Pathway | Axon guidance, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Interaction between L1 and Ankyrins, organism-specific biosystem; L1CAM interactions, organism-specific biosystem; SIDS Susceptibility Pathways, organism-specific biosystem; |
| MIM | 600163 |
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