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Rat Scn5a ORF Clone(NM_013125.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR377871

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Product Information

Gene Information

Cat. No. CDCR377871
Product Type ORF Clone
Gene Abbr Scn5a
Species Rat
Tag C-terminal Myc-DDK
ORF Size 6060 bp
Vector pCMV6-Entry
Target Gene SCN5A
Background The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene have been associated with long QT syndrome type 3 (LQT3), atrial fibrillation, cardiomyopathy, and Brugada syndrome 1, all autosomal dominant cardiac diseases. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, May 2022]
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