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Rat Nbn ORF Clone(NM_138873.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR381344

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Product Information

Gene Information

Cat. No. CDCR381344
Product Type ORF Clone
Gene Abbr Nbn
Species Rat
Tag C-terminal Myc-DDK
ORF Size 2253 bp
Vector pCMV6-Entry
Target Gene NBN
Background Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008]
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