shRNA set against Rat Nbn (NM_138873.2)

Name: shRNA set against Rat Nbn (NM_138873.2)
SKU: SHH349668
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHH349668

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Gene Information

Cat. No.	SHH349668
Description	The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr	Nbn
Gene Name	Nbn nibrin [ Mus musculus ]
Species	Rat
Report Gene	GFP
Storage	The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.

Gene Name	Nbn nibrin [ Mus musculus ]
Gene Symbol	Nbn
Synonyms	Nbs1
Gene Description	nibrin
Gene ID	27354
Uni Prot ID	A2AMG6
m RNA Refseq	NM_013752.3
Protein Refseq	NP_038780.3
Chromosome Location	4; 4 A
Function	damaged DNA binding; protein N-terminus binding; transcription factor binding;
Pathway	ATM mediated phosphorylation of repair proteins, organism-specific biosystem; ATM mediated response to DNA double-strand break, organism-specific biosystem; Assembly of the RAD50-MRE11-NBS1 complex at DNA double-strand breaks, organism-specific biosystem; BRCA1-associated genome surveillance complex (BASC), organism-specific biosystem; DNA Repair, organism-specific biosystem; Double-Strand Break Repair, organism-specific biosystem; Homologous Recombination Repair, organism-specific biosystem;

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