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Human NBN ORF clone (NM_002485.4)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCL136679

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Gene Information

Cat. No. CDCL136679
Description Homo sapiens nibrin (NBN), mRNA.
Product Type ORF clone
Gene Abbr NBN
Gene Name NBN nibrin [ Homo sapiens ]
Species Human
ORF Size 2265bp
Format purified plasmid
Vector pDONR
Warning Please note that the protein for this clone has been annotated or predicted in the UNIPROT database to have a signal peptide. Placing a tag at the N-terminus of this protein may result in loss of the signal peptide function.
Gene Name NBN nibrin [ Homo sapiens ]
Gene Symbol NBN
Synonyms ATV; NBS; P95; NBS1; AT-V1; AT-V2
Gene Description nibrin
Gene ID 4683
Uni Prot ID O60934
m RNA Refseq NM_002485.4
Protein Refseq NP_002476.2
Chromosome Location 8q21
Function contributes_to ATP-dependent DNA helicase activity; contributes_to damaged DNA binding; protein N-terminus binding; protein binding; transcription factor binding;
Pathway ATM mediated phosphorylation of repair proteins, organism-specific biosystem; ATM mediated response to DNA double-strand break, organism-specific biosystem; Assembly of the RAD50-MRE11-NBS1 complex at DNA double-strand breaks, organism-specific biosystem; BARD1 signaling events, organism-specific biosystem; BRCA1-associated genome surveillance complex (BASC), organism-specific biosystem; DNA Repair, organism-specific biosystem; DNA damage response, organism-specific biosystem;
MIM 602667
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