Rat Ctnnb1 cDNA Clone(NM_053357.2)

Name: Rat Ctnnb1 cDNA Clone(NM_053357.2)
SKU: CDFR013112
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR013112

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Product Information

Gene Information

Cat. No.	CDFR013112
Description	NativeORF clone of Rattus norvegicus catenin (cadherin associated protein), beta 1 (Ctnnb1) as transfection-ready DNA NM_053357.2
Product Type	cDAN Clone
Gene Abbr	Ctnnb1
Species	Rat
Vector	pCMV6Entry

Target Gene

CTNNB1

Background

The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]

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