Panoply™ Human NR1H3 Over-expressing Stable Cell Line

Name: Panoply™ Human NR1H3 Over-expressing Stable Cell Line
SKU: CSC-SC010588
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-SC010588

Host Cell : HEK293 (CHO and other cell types are also available) Size : >1x10⁶ frozen cells/vial

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Cell Line Information

Cell Culture Information

Safety and Packaging

Gene Information

Cat. No.	CSC-SC010588
Description	Using Creative Biogene's proprietary lentiviral vectors, we subclone the target gene into lentivector, generate the lentivirus particles, sequentially infect the cell line HEK293 (other cell types are also available according to your requirements), and select the clones constantly expressing target gene at high level.
Target Gene	NR1H3
Gene Species	Homo sapiens (Human)
Host Cell	HEK293 (CHO and other cell types are also available)
Host Cell Species	Species varies
Applications	1. Gene expression studies 2. Signaling pathway research 3. Drug screening and toxicology 4. Disease research
Size	2 × 10^6 cells / vial
Stability	Validated for at least 10 passages
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid nitrogen
Shipping	Dry Ice

Revival

Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media.

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	NR1H3 nuclear receptor subfamily 1, group H, member 3 [ Homo sapiens ]
Gene Symbol	NR1H3
Synonyms	LXRA; LXR-a; RLD-1
Gene Description	nuclear receptor subfamily 1, group H, member 3
GeneID	10062
Uni ProtID	Q8IW13
mRNA Refseq	NM_001130102.2
Protein Refseq	NP_001123574.1
Chromosome Location	11p11.2
Function	DNA binding; cholesterol binding; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; protein binding; protein heterodimerization activity; retinoid X receptor binding; sequence-specific DNA binding; steroid hormone receptor activity; sterol response element binding; transcription coactivator activity; transcription regulatory region DNA binding; contributes_to transcription regulatory region DNA binding; zinc ion binding;
Pathway	Adipogenesis, organism-specific biosystem; Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem; Hepatitis C, organism-specific biosystem; Hepatitis C, conserved biosystem; Nuclear Receptor transcription pathway, organism-specific biosystem; Nuclear Receptors, organism-specific biosystem;
MIM	602423

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