Transfected Stable Cell Lines
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Cat. No. : RSNK-019
| Cat. No. | RSNK-019 |
| Description | 5-Methoxy-UTP is a modified NTP for incorporation into messenger RNAs (mRNA) using T7 RNA Polymerase. The Incorporation of 5-Methoxy-UTP can reduce the mRNA immunogenicity. |
| Alias | 5-Methoxyuridine-5’-Triphosphate |
| Applications | In vitro transcription |
| Molecular Formula | C10H17N2O16P3 |
| Molecular Weight | 514.1 |
| Size | 1 µmol, 5 µmol |
| Purity | ≥90% |
| Storage | Store at -20°C. |
A: 5-Methoxy-UTP is a modified nucleotide that contains a methoxy group (-OCH3) at the 5' position of the uridine base. It is a substrate for RNA polymerases and can be incorporated into RNA molecules during transcription.
A: Yes. 5-Methody-UTP can be used for labeling RNA molecules for visualization or detection purposes, as the methoxy group can be conjugated to fluorescent dyes or other labeling molecules.
A: 5-Methoxy-UTP can be used for structural functional research of RNA, as it can generate modified RNA molecules with altered properties. For example, the incorporation of 5-methoxy-UTP can alter the tertiary structure of RNA, affect RNA protein interactions, or alter RNA stability.
A: 5-Methoxy-UTP has been shown to cross the blood-brain barrier more efficiently than other nucleoside analogs, making it a potential candidate for the treatment of neurological disorders.
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5-Methoxy-UTP can protect RNA from degradation by RNases compared to unmodified UTP. I recommend it.
This is particularly useful for experiments that require high RNA labeling efficiency, such as microarray analysis or RNA sequencing. I like it.
Better reverse transcription - 5-MeOTTP can enhance reverse transcription efficiency when used as a substrate for cDNA synthesis. I have repurchased it multiple times.
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