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SM 324405

For research use only. Not intended for any clinical use.
Cat.No.
VAR-033
Description
SM 324405 is a potent TLR7 agonist. It exhibits selectivity activity for TLR7 over TLR8. In addition, SM 324405 Induces IFN-α and -γ expression in human PBMCs and mouse splenocytes, and inhibits IL-5 production in human PBMCs in vitro.
Product Type
Toll-like Receptor Agonists
Purity
≥98%
Storage
Store at 4°C.

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Q & A

Customer Reviews

Customer Q&As
What is the target receptor of SM 324405?

A: SM 324405 is an effective TLR7 agonist, which has better selectivity for TLR7 than TLR8.

Is the service attitude good?

A: The service attitude is good, responsive, and communication is generally through phone and chat software.

Is it transported at room temperature?

A: No, during transportation, the reagent is placed in a foam box with many ice bags to ensure the activity of the reagent.

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Customer Reviews
Expresses IFN

SM 324405 can induce the expression of IFN-α and IFN-γ in human PBMC and mouse splenocytes.

United States

01/12/2020

Inhibits IL-5

We have successfully inhibited the production of IL-5 in human PBMCs in vitro using this reagent.

United States

04/11/2021

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