Transfected Stable Cell Lines
Reliable | High-Performance | Wide Rage
Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : SHH417744
| Cat. No. | SHH417744 |
| Description | The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells. |
| Gene Abbr | SREBF2 |
| Gene Name | Srebf2 sterol regulatory element binding factor 2 [ Mus musculus ] |
| Species | Mouse |
| Report Gene | GFP |
| Storage | The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C. |
| Gene Name | Srebf2 sterol regulatory element binding factor 2 [ Mus musculus ] |
| Gene Symbol | Srebf2 |
| Synonyms | nuc; lop13; SREBP2; bHLHd2; SREBP-2; AI608257; SREBP2gc |
| Gene Description | sterol regulatory element binding factor 2 |
| Gene ID | 20788 |
| Uni Prot ID | Q3U1N2 |
| m RNA Refseq | NM_033218.1 |
| Protein Refseq | NP_150087.1 |
| Chromosome Location | 15 E1; 15 |
| Function | DNA binding; E-box binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding; chromatin binding; protein C-terminus binding; protein binding; protein dimerization activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; |
| Pathway | Activation of Gene Expression by SREBP (SREBF), organism-specific biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; PPARA Activates Gene Expression, organism-specific biosystem; Regulation of Cholesterol Biosynthesis by SREBP (SREBF), organism-specific biosystem; Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha), organism-specific biosystem; |
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