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shRNA set against Mouse SREBF2 (NM_033218.1)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH417744

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Gene Information

Cat. No. SHH417744
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr SREBF2
Gene Name Srebf2 sterol regulatory element binding factor 2 [ Mus musculus ]
Species Mouse
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name Srebf2 sterol regulatory element binding factor 2 [ Mus musculus ]
Gene Symbol Srebf2
Synonyms nuc; lop13; SREBP2; bHLHd2; SREBP-2; AI608257; SREBP2gc
Gene Description sterol regulatory element binding factor 2
Gene ID 20788
Uni Prot ID Q3U1N2
m RNA Refseq NM_033218.1
Protein Refseq NP_150087.1
Chromosome Location 15 E1; 15
Function DNA binding; E-box binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding; chromatin binding; protein C-terminus binding; protein binding; protein dimerization activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity;
Pathway Activation of Gene Expression by SREBP (SREBF), organism-specific biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; PPARA Activates Gene Expression, organism-specific biosystem; Regulation of Cholesterol Biosynthesis by SREBP (SREBF), organism-specific biosystem; Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha), organism-specific biosystem;
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