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Panoply™ Human SREBF2 Knockdown Stable Cell Line

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Cat.No.
CSC-DC015142
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Gene
SREBF2
Gene Species
Human
Host Cell
HEK293 (Hela and other cell types are also available)
Growth Properties
Adherent
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Size
2 × 10^6 cells / vial
Storage
Liquid Nitrogen
Ship
Dry Ice
Gene Information
Official Symbol
SREBF2
Synonyms
SREBP2; bHLHd2
GeneID
mRNA Refseq
Protein Refseq
MIM
UniProt ID
Q12772
Chromosome Location
22q13
Pathway
Activation of Gene Expression by SREBP (SREBF), organism-specific biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; PPARA Activates Gene Expression, organism-specific biosystem; Regulation of Cholesterol Biosynthesis by SREBP (SREBF), organism-specific biosystem; Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha), organism-specific biosystem;
Function
NOT C-8 sterol isomerase activity; E-box binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding; protein C-terminus binding; protein binding; protein dimerization activity;

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