shRNA set against Human SREBF2 (NM_004599.2)

Name: shRNA set against Human SREBF2 (NM_004599.2)
SKU: SHH417740
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHH417740

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Product Information

Gene Information

Cat. No.	SHH417740
Description	The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr	SREBF2
Gene Name	SREBF2 sterol regulatory element binding transcription factor 2 [ Homo sapiens ]
Species	Human
Report Gene	GFP
Storage	The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.

Gene Name	SREBF2 sterol regulatory element binding transcription factor 2 [ Homo sapiens ]
Gene Symbol	SREBF2
Synonyms	SREBP2; bHLHd2
Gene Description	sterol regulatory element binding transcription factor 2
Gene ID	6721
Uni Prot ID	Q12772
m RNA Refseq	NM_004599.2
Protein Refseq	NP_004590.2
Chromosome Location	22q13
Function	NOT C-8 sterol isomerase activity; E-box binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding; protein C-terminus binding; protein binding; protein dimerization activity;
Pathway	Activation of Gene Expression by SREBP (SREBF), organism-specific biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; PPARA Activates Gene Expression, organism-specific biosystem; Regulation of Cholesterol Biosynthesis by SREBP (SREBF), organism-specific biosystem; Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha), organism-specific biosystem;
MIM	600481

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