shRNA set against Mouse MDM2 (NM_010786.3)

Name: shRNA set against Mouse MDM2 (NM_010786.3)
SKU: SHH339679
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHH339679

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Gene Information

Cat. No.	SHH339679
Description	The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr	MDM2
Gene Name	Mdm2 transformed mouse 3T3 cell double minute 2 [ Mus musculus ]
Species	Mouse
Report Gene	GFP
Storage	The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.

Gene Name	Mdm2 transformed mouse 3T3 cell double minute 2 [ Mus musculus ]
Gene Symbol	MDM2
Synonyms	Mdm-2; AA415488; 1700007J15Rik
GeneID	17246
Uni ProtID	P23804
mRNA Refseq	NM_010786.3
Protein Refseq	NP_034916.1
Chromosome Location	10 C1-C3; 10 66.0 cM
Function	enzyme binding; identical protein binding; ligase activity; metal ion binding; p53 binding; p53 binding; peroxisome proliferator activated receptor binding; protein binding; scaffold protein binding; ubiquitin-protein ligase activity; ubiquitin-protein ligase activity; zinc ion binding;
Pathway	AKT phosphorylates targets in the cytosol, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; Apoptosis, organism-specific biosystem; Bladder cancer, organism-specific biosystem; Bladder cancer, conserved biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle Checkpoints, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, conserved biosystem; Cell cycle signaling pathway, organism-specific biosystem; Chronic myeloid leukemia, organism-specific biosystem; Chronic myeloid leukemia, conserved biosystem; Constitutive PI3K/AKT Signaling in Cancer, organism-specific biosystem; DAP12 interactions, organism-specific biosystem; DAP12 signaling, organism-specific biosystem; Disease, organism-specific biosystem; Downstream Signaling Events Of B Cell Receptor (BCR), organism-specific biosystem; Downstream signal transduction, organism-specific biosystem; Downstream signaling of activated FGFR, organism-specific biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; Epstein-Barr virus infection, organism-specific biosystem; Epstein-Barr virus infection, conserved biosystem; G1 to S cell cycle control, organism-specific biosystem; G1/S DNA Damage Checkpoints, organism-specific biosystem; GAB1 signalosome, organism-specific biosystem; Glioma, organism-specific biosystem; Glioma, conserved biosystem; Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity, organism-specific biosystem; Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; Melanoma, organism-specific biosystem; Melanoma, conserved biosystem; NGF signalling via TRKA from the plasma membrane, organism-specific biosystem; Neuronal System, organism-specific biosystem; Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell, organism-specific biosystem; PI-3K cascade, organism-specific biosystem; PI3K events in ERBB2 signaling, organism-specific biosystem; PI3K events in ERBB4 signaling, organism-specific biosystem; PI3K-Akt signaling pathway, organism-specific biosystem; PI3K-Akt signaling pathway, conserved biosystem; PI3K/AKT Signaling in Cancer, organism-specific biosystem; PI3K/AKT activation, organism-specific biosystem; PI3K/Akt/mTOR signaling pathway, organism-specific biosystem; PIP3 activates AKT signaling, organism-specific biosystem; Pathways in cancer, organism-specific biosystem; PluriNetWork, organism-specific biosystem; Prostate cancer, organism-specific biosystem; Prostate cancer, conserved biosystem; Senescence and Autophagy, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by EGFR, organism-specific biosystem; Signaling by EGFR in Cancer, organism-specific biosystem; Signaling by ERBB2, organism-specific biosystem; Signaling by ERBB4, organism-specific biosystem; Signaling by FGFR, organism-specific biosystem; Signaling by FGFR in disease, organism-specific biosystem; Signaling by PDGF, organism-specific biosystem; Signaling by SCF-KIT, organism-specific biosystem; Signaling by the B Cell Receptor (BCR), organism-specific biosystem; Signalling by NGF, organism-specific biosystem; Stabilization of p53, organism-specific biosystem; Trafficking of AMPA receptors, organism-specific biosystem; Transcriptional misregulation in cancer, organism-specific biosystem; Transcriptional misregulation in cancer, conserved biosystem; Transmission across Chemical Synapses, organism-specific biosystem; Tryptophan metabolism, organism-specific biosystem; Ubiquitin mediated proteolysis, organism-specific biosystem; Ubiquitin mediated proteolysis, conserved biosystem; Viral carcinogenesis, organism-specific biosystem; Viral carcinogenesis, conserved biosystem; p53 signaling pathway, organism-specific biosystem; p53 signaling pathway, conserved biosystem; p53-Dependent G1 DNA Damage Response, organism-specific biosystem; p53-Dependent G1/S DNA damage checkpoint, organism-specific biosystem;

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