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Panoply™ Human MDM2 Knockdown Stable Cell Line

Cat.No.
CSC-DC009340
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
MDM2
Synonyms
HDMX; hdm2; ACTFS
Gene ID
UniProt ID
Q00987
mRNA Refseq
Protein Refseq
Chromosome Location
12q14.3-q15
Function
enzyme binding; identical protein binding; p53 binding; protein binding; scaffold protein binding; ubiquitin-protein ligase activity; ubiquitin-protein ligase activity; zinc ion binding;
Pathway
AKT phosphorylates targets in the cytosol, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; Apoptosis, organism-specific biosystem; Aurora A signaling, organism-specific biosystem; Bladder cancer, organism-specific biosystem; Bladder cancer, conserved biosystem;
MIM

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