shRNA set against Mouse GCH1 (NM_008102.3)

Name: shRNA set against Mouse GCH1 (NM_008102.3)
SKU: SHH300002
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHH300002

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Product Information

Gene Information

Cat. No.	SHH300002
Description	The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr	GCH1
Gene Name	Gch1 GTP cyclohydrolase 1 [ Mus musculus ]
Species	Mouse
Report Gene	GFP
Storage	The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.

Gene Name	Gch1 GTP cyclohydrolase 1 [ Mus musculus ]
Gene Symbol	Gch1
Synonyms	Gch; GTPCH; GTP-CH
Gene Description	GTP cyclohydrolase 1
Gene ID	14528
Uni Prot ID	Q05915
m RNA Refseq	NM_008102.3
Protein Refseq	NP_032128.1
Chromosome Location	14 C2-3; 14 19.5 cM
Function	GTP binding; GTP cyclohydrolase I activity; GTP cyclohydrolase I activity; GTP-dependent protein binding; calcium ion binding; catalytic activity; coenzyme binding; hydrolase activity; metal ion binding; nucleotide binding; protein homodimerization activity; zinc ion binding;
Pathway	Folate biosynthesis, organism-specific biosystem; Folate biosynthesis, conserved biosystem; Metabolism, organism-specific biosystem; Metabolism of nitric oxide, organism-specific biosystem; Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation, organism-specific biosystem; eNOS activation and regulation, organism-specific biosystem; tetrahydrobiopterin biosynthesis I, organism-specific biosystem;

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