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GCH1 miRNA 3'UTR clone

For research use only. Not intended for any clinical use.

Cat. No. :   MiUTR3H-03196

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Gene Information

Cat. No. MiUTR3H-03196
Description 3'UTR clone of GTP cyclohydrolase 1 (GCH1) transcript variant 2 for miRNA target validation
Gene Abbr GCH1
Gene Name GCH1 GTP cyclohydrolase 1 [ Homo sapiens ]
Species Human
Reporter luciferase-RFP
Promoter SV40
Resistance Neo/Kanr
Selection Marker Neomycin
Size The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials.
Vector pMirTarget
Vector Type plasmid
Storage -20 ℃
Gene Name GCH1 GTP cyclohydrolase 1 [ Homo sapiens ]
Gene Symbol GCH1
Synonyms GCH; DYT5; DYT14; DYT5a; GTPCH1; HPABH4B; GTP-CH-1
Gene Description GTP cyclohydrolase 1 (dopa-responsive dystonia)
Gene ID 2643
Uni Prot ID P30793
m RNA Refseq NM_000161.2
Protein Refseq NP_000152.1
Chromosome Location 14q22.1-q22.2
Function GTP binding; GTP cyclohydrolase I activity; NOT GTP cyclohydrolase I activity; GTP-dependent protein binding; calcium ion binding; coenzyme binding; protein binding; protein homodimerization activity; zinc ion binding;
Pathway Folate biosynthesis, organism-specific biosystem; Folate biosynthesis, conserved biosystem; Metabolism, organism-specific biosystem; Metabolism of nitric oxide, organism-specific biosystem; Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation, organism-specific biosystem; eNOS activation and regulation, organism-specific biosystem; tetrahydrobiopterin biosynthesis I, organism-specific biosystem;
MIM 600225
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