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Human GCH1 ORF clone (NM_001024070.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCL110997

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Product Information

Gene Information

Cat. No. CDCL110997
Description Homo sapiens GTP cyclohydrolase 1 (GCH1), transcript variant 3, mRNA.
Product Type ORF clone
Gene Abbr GCH1
Gene Name GCH1 GTP cyclohydrolase 1 [ Homo sapiens ]
Species Human
ORF Size 702bp
Format purified plasmid
Vector pDONR
Warning Please note that the protein for this clone has been annotated or predicted in the UNIPROT database to have a signal peptide. Placing a tag at the N-terminus of this protein may result in loss of the signal peptide function.
Gene Name GCH1 GTP cyclohydrolase 1 [ Homo sapiens ]
Gene Symbol GCH1
Synonyms GCH; DYT5; DYT14; DYT5a; GTPCH1; HPABH4B; GTP-CH-1
Gene Description GTP cyclohydrolase 1 (dopa-responsive dystonia)
Gene ID 2643
Uni Prot ID P30793
m RNA Refseq NM_000161.2
Protein Refseq NP_000152.1
Chromosome Location 14q22.1-q22.2
Function GTP binding; GTP cyclohydrolase I activity; NOT GTP cyclohydrolase I activity; GTP-dependent protein binding; calcium ion binding; coenzyme binding; protein binding; protein homodimerization activity; zinc ion binding;
Pathway Folate biosynthesis, organism-specific biosystem; Folate biosynthesis, conserved biosystem; Metabolism, organism-specific biosystem; Metabolism of nitric oxide, organism-specific biosystem; Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation, organism-specific biosystem; eNOS activation and regulation, organism-specific biosystem; tetrahydrobiopterin biosynthesis I, organism-specific biosystem;
MIM 600225
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