Tel: 1-631-626-9181 (USA)   44-207-097-1828 (Europe)
  Email:

Panoply™ Human GCH1 Knockdown Stable Cell Line

Cat.No.
CSC-DC006161
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
GCH1
Synonyms
GCH; DYT5; DYT14; DYT5a; GTPCH1; HPABH4B; GTP-CH-1
Gene Description
GTP cyclohydrolase 1 (dopa-responsive dystonia)
Gene ID
UniProt ID
P30793
mRNA Refseq
Protein Refseq
Chromosome Location
14q22.1-q22.2
Function
GTP binding; GTP cyclohydrolase I activity; NOT GTP cyclohydrolase I activity; GTP-dependent protein binding; calcium ion binding; coenzyme binding; protein binding; protein homodimerization activity; zinc ion binding;
Pathway
Folate biosynthesis, organism-specific biosystem; Folate biosynthesis, conserved biosystem; Metabolism, organism-specific biosystem; Metabolism of nitric oxide, organism-specific biosystem; Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation, organism-specific biosystem; eNOS activation and regulation, organism-specific biosystem; tetrahydrobiopterin biosynthesis I, organism-specific biosystem;
MIM

Quick Inquiry

   Please input "biogene" as verification code.