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Panoply™ Human GCH1 Knockdown Stable Cell Line

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Cat.No.
CSC-DC006161
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Gene
GCH1
Gene Species
Human
Host Cell
HEK293 (Hela and other cell types are also available)
Growth Properties
Adherent
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Size
2 × 10^6 cells / vial
Storage
Liquid Nitrogen
Ship
Dry Ice
Gene Information
Official Symbol
GCH1
Synonyms
GCH; DYT5; DYT14; DYT5a; GTPCH1; HPABH4B; GTP-CH-1
GeneID
mRNA Refseq
Protein Refseq
MIM
UniProt ID
P30793
Chromosome Location
14q22.1-q22.2
Pathway
Folate biosynthesis, organism-specific biosystem; Folate biosynthesis, conserved biosystem; Metabolism, organism-specific biosystem; Metabolism of nitric oxide, organism-specific biosystem; Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation, organism-specific biosystem; eNOS activation and regulation, organism-specific biosystem; tetrahydrobiopterin biosynthesis I, organism-specific biosystem;
Function
GTP binding; GTP cyclohydrolase I activity; NOT GTP cyclohydrolase I activity; GTP-dependent protein binding; calcium ion binding; coenzyme binding; protein binding; protein homodimerization activity; zinc ion binding;

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