shRNA set against Human XRCC6 (NM_001469.3)

Name: shRNA set against Human XRCC6 (NM_001469.3)
SKU: SHH448140
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHH448140

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Product Information

Gene Information

Cat. No.	SHH448140
Description	The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr	XRCC6
Gene Name	XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 [ Homo sapiens ]
Species	Human
Report Gene	GFP
Storage	The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.

Gene Name	XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 [ Homo sapiens ]
Gene Symbol	XRCC6
Synonyms	ML8; KU70; TLAA; CTC75; CTCBF; G22P1
Gene Description	X-ray repair complementing defective repair in Chinese hamster cells 6 (Ku autoantigen, 70kDa)
Gene ID	2547
Uni Prot ID	B1AHC8
m RNA Refseq	NM_001469.3
Protein Refseq	NP_001460.1
Chromosome Location	22q13.2
Function	5-deoxyribose-5-phosphate lyase activity; ATP binding; ATP-dependent DNA helicase activity; DNA binding; double-stranded DNA binding; contributes_to double-stranded telomeric DNA binding; protein C-terminus binding; protein binding; transcription regulatory region DNA binding;
Pathway	2-LTR circle formation, organism-specific biosystem; BARD1 signaling events, organism-specific biosystem; Coregulation of Androgen receptor activity, organism-specific biosystem; DNA Repair, organism-specific biosystem; DNA-PK complex, organism-specific biosystem; Disease, organism-specific biosystem; Double-Strand Break Repair, organism-specific biosystem;
MIM	152690

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