Human XRCC6 Knockdown Cell Line - Glioma

Name: Human XRCC6 Knockdown Cell Line - Glioma
SKU: CSC-RK0242
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RK0242

Host Cell : Glioma Validation : Real-Time RCR

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Cell Line Information

Safety and Packaging

Gene Information

Cat. No.	CSC-RK0242
Description	This cell line is engineered to stably express shRNA targeting human XRCC6.
Target Gene	XRCC6
Host Cell	Glioma
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Storage	Liquid nitrogen
Shipping	Dry ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 [ Homo sapiens ]
Gene Symbol	XRCC6
Synonyms	ML8; KU70; TLAA; CTC75; CTCBF; G22P1
Gene Description	X-ray repair complementing defective repair in Chinese hamster cells 6 (Ku autoantigen, 70kDa)
Gene ID	2547
Uni Prot ID	B1AHC8
m RNA Refseq	NM_001469.3
Protein Refseq	NP_001460.1
Chromosome Location	22q13.2
Function	5-deoxyribose-5-phosphate lyase activity; ATP binding; ATP-dependent DNA helicase activity; DNA binding; double-stranded DNA binding; contributes_to double-stranded telomeric DNA binding; protein C-terminus binding; protein binding; transcription regulatory region DNA binding;
Pathway	2-LTR circle formation, organism-specific biosystem; BARD1 signaling events, organism-specific biosystem; Coregulation of Androgen receptor activity, organism-specific biosystem; DNA Repair, organism-specific biosystem; DNA-PK complex, organism-specific biosystem; Disease, organism-specific biosystem; Double-Strand Break Repair, organism-specific biosystem;
MIM	152690

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