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XRCC6

Official Full Name
X-ray repair cross complementing 6
Organism
Homo sapiens
GeneID
2547
Background
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008]
Synonyms
ML8; KU70; TLAA; CTC75; CTCBF; G22P1;

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