shRNA set against Human Rest (NM_005612.4)

Name: shRNA set against Human Rest (NM_005612.4)
SKU: SHH392032
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHH392032

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Product Information

Gene Information

Cat. No.	SHH392032
Description	The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr	Rest
Gene Name	REST RE1-silencing transcription factor [ Homo sapiens ]
Species	Human
Report Gene	GFP
Storage	The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.

Gene Name	REST RE1-silencing transcription factor [ Homo sapiens ]
Gene Symbol	REST
Synonyms	REST; RE1-silencing transcription factor; NRSF; XBR; repressor binding to the X2 box; neural-restrictive silencer factor; neuron restrictive silencer factor;
GeneID	5978
Uni ProtID	Q13127
mRNA Refseq	BC132859
Chromosome Location	4q12
Function	DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; calcium channel activity; chromatin binding; core promoter binding; core promoter sequence-specific DNA binding; metal ion binding; outward rectifier potassium channel activity; protein binding; protein complex binding; sequence-specific DNA binding transcription factor activity; transcription factor binding; transcription regulatory region DNA binding; zinc ion binding;
Pathway	Huntingtons disease, organism-specific biosystem; Huntingtons disease, conserved biosystem; SIDS Susceptibility Pathways, organism-specific biosystem;
MIM	600571

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