Transfected Stable Cell Lines
Reliable | High-Performance | Wide Rage
Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDFR012920
| Cat. No. | CDFR012920 |
| Description | NativeORF clone of Rattus norvegicus RE1-silencing transcription factor (Rest) as transfection-ready DNA NM_031788.1 |
| Product Type | cDAN Clone |
| Gene Abbr | Rest |
| Species | Rat |
| Vector | pCMV6Entry |
| Target Gene | REST |
| Background | This gene was initially identified as a transcriptional repressor that represses neuronal genes in non-neuronal tissues. However, depending on the cellular context, this gene can act as either an oncogene or a tumor suppressor. The encoded protein is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regulator of neurogenesis. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2018] |
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