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Rat Rest cDNA Clone(NM_031788.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR012920

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Gene Information

Cat. No. CDFR012920
Description NativeORF clone of Rattus norvegicus RE1-silencing transcription factor (Rest) as transfection-ready DNA NM_031788.1
Product Type cDAN Clone
Gene Abbr Rest
Species Rat
Vector pCMV6Entry
Target Gene REST
Background This gene was initially identified as a transcriptional repressor that represses neuronal genes in non-neuronal tissues. However, depending on the cellular context, this gene can act as either an oncogene or a tumor suppressor. The encoded protein is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regulator of neurogenesis. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2018]
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