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Mouse Rest cDNA Clone(NM_011263.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFL011414

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Product Information

Gene Information

Cat. No. CDFL011414
Product Type cDNA clone
Gene Abbr Rest
Species Mouse
Size 10 ug
Vector pCMV6Entry
Target Gene REST
Background This gene was initially identified as a transcriptional repressor that represses neuronal genes in non-neuronal tissues. However, depending on the cellular context, this gene can act as either an oncogene or a tumor suppressor. The encoded protein is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regulator of neurogenesis. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2018]
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