shRNA set against Human PARP1(NM_001618.3)

Name: shRNA set against Human PARP1(NM_001618.3)
SKU: SHR088494
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHR088494

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Product Information

Gene Information

Cat. No.	SHR088494
Description	Each set contains 4 shRNA expression constructs. The hairpin consists of a 7 base loop and 19~29 base stem optimized for the specific gene sequence. The sequences of 19~29mer shRNAi will be delivered with shRNA clones.
Gene Abbr	PARP1
Gene Name	PARP1 poly (ADP-ribose) polymerase 1 [ Homo sapiens ]
Species	Human
Report Gene	eGFP
Content	Each set contains 4 shRNA expression constructs.
Promoter	H1
Selection Marker	Puromycin
Format	5 μg purified plasmid
Unit Size	5 μg

Gene Name	PARP1 poly (ADP-ribose) polymerase 1 [ Homo sapiens ]
Gene Symbol	PARP1
Synonyms	PARP; PPOL; ADPRT; ARTD1; ADPRT1; PARP-1; ADPRT 1; pADPRT-1
Gene Description	poly (ADP-ribose) polymerase family, member 1
GeneID	142
Uni ProtID	P09874
mRNA Refseq	NM_001618.3
Protein Refseq	NP_001609.2
Chromosome Location	1q41-q42
Function	DNA binding; NAD binding; NAD+ ADP-ribosyltransferase activity; NAD+ ADP-ribosyltransferase activity; protein N-terminus binding; protein binding; transcription factor binding; zinc ion binding;
Pathway	BER complex, organism-specific biosystem; BER complex, conserved biosystem; Base excision repair, organism-specific biosystem; Base excision repair, conserved biosystem; Caspase cascade in apoptosis, organism-specific biosystem; Downregulation of SMAD2/3:SMAD4 transcriptional activity, organism-specific biosystem; FAS pathway and Stress induction of HSP regulation, organism-specific biosystem;
MIM	173870

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