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shRNA set against Mouse PARP1 (NM_007415.2)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH370816

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Gene Information

Cat. No. SHH370816
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr PARP1
Gene Name Parp1 poly (ADP-ribose) polymerase family, member 1 [ Mus musculus ]
Species Mouse
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name Parp1 poly (ADP-ribose) polymerase family, member 1 [ Mus musculus ]
Gene Symbol Parp1
Synonyms PARP; PPOL; ARTD1; Adprp; Adprt1; C80510; parp-1; sPARP-1; AI893648; 5830444G22Rik
Gene Description poly (ADP-ribose) polymerase family, member 1
GeneID 11545
Uni ProtID Q921K2
mRNA Refseq NM_007415.2
Protein Refseq NP_031441.2
Chromosome Location 1 H5; 1 98.6 cM
Function NAD binding; NAD+ ADP-ribosyltransferase activity; protein N-terminus binding; protein binding; transcription factor binding;
Pathway BER complex, organism-specific biosystem; BER complex, conserved biosystem; Base excision repair, organism-specific biosystem; Base excision repair, conserved biosystem; Downregulation of SMAD2/3:SMAD4 transcriptional activity, organism-specific biosystem; FAS pathway and Stress induction of HSP regulation, organism-specific biosystem; Gene Expression, organism-specific biosystem;
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