shRNA set against Human LCK (NM_005356.3)

Name: shRNA set against Human LCK (NM_005356.3)
SKU: SHH328975
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHH328975

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Product Information

Gene Information

Cat. No.	SHH328975
Description	The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr	LCK
Gene Name	LCK lymphocyte-specific protein tyrosine kinase [ Homo sapiens ]
Species	Human
Report Gene	GFP
Storage	The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.

Gene Name	LCK lymphocyte-specific protein tyrosine kinase [ Homo sapiens ]
Gene Symbol	LCK
Synonyms	LSK; YT16; p56lck; pp58lck
Gene Description	lymphocyte-specific protein tyrosine kinase
Gene ID	3932
Uni Prot ID	P06239
m RNA Refseq	NM_001042771.1
Protein Refseq	NP_001036236.1
Chromosome Location	1p34.3
Function	ATP binding; ATPase binding; CD4 receptor binding; CD8 receptor binding; SH2 domain binding; SH2 domain binding; glycoprotein binding; non-membrane spanning protein tyrosine kinase activity; phosphatidylinositol 3-kinase binding; protein C-terminus binding; protein binding; protein kinase binding; protein serine/threonine phosphatase activity; protein serine/threonine phosphatase activity; protein tyrosine kinase activity; protein tyrosine kinase activity; protein tyrosine kinase activity; protein tyrosine kinase activity;
Pathway	Adaptive Immune System, organism-specific biosystem; Alpha-synuclein signaling, organism-specific biosystem; Atypical NF-kappaB pathway, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; CD28 co-stimulation, organism-specific biosystem; CD28 dependent PI3K/Akt signaling, organism-specific biosystem; CD28 dependent Vav1 pathway, organism-specific biosystem;
MIM	153390

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