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Rat Lck cDNA Clone(NM_001100709.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR005330

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Gene Information

Cat. No. CDFR005330
Description NativeORF clone of Rattus norvegicus lymphocyte-specific protein tyrosine kinase (Lck) as transfection-ready DNA NM_001100709.1
Product Type cDAN Clone
Gene Abbr Lck
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene LCK
Background This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Aug 2016]
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