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LCK


Official Full Name
LCK proto-oncogene, Src family tyrosine kinase
Organism
Homo sapiens
Gene ID
3932
Background
This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Aug 2016]
Synonyms
LSK; YT16; IMD22; p56lck; pp58lck

Cat.No. Product Name Price
SHH328975 shRNA set against Human LCK (NM_005356.3) Inquiry
SHH328979 shRNA set against Mouse LCK (NM_010693.3) Inquiry
SHH144245 shRNA set against Human LCK(NM_001042771.1) Inquiry
SHH328983 shRNA set against Rat LCK (NM_001100709.1) Inquiry
SHW006106 shRNA set against Danio rerio LCK (NM_001001596) Inquiry
SHW009646 shRNA set against Danio rerio LCK (NM_001040328) Inquiry
Cat.No. Product Name Price
CDCL185110 Human Lck ORF clone(NM_001042771.1) Inquiry
CDCS407144 Human LCK ORF Clone (BC013200) Inquiry
CDFH010243 Human LCK cDNA Clone(NM_001042771.1) Inquiry
CDFR005330 Rat Lck cDNA Clone(NM_001100709.1) Inquiry
MiUTR1H-05607 LCK miRNA 3'UTR clone Inquiry
MiUTR3H-01353 LCK miRNA 3'UTR clone Inquiry
CDCB167581 Danio rerio LCK ORF Clone (NM_001001596) Inquiry
CDCB171121 Danio rerio LCK ORF Clone (NM_001040328) Inquiry
CDCB188398 Rabbit LCK ORF clone (XM_002720629.2) Inquiry
CDCL126475 Mouse Lck ORF clone (NM_001162432.1) Inquiry
CDCL126479 Human LCK ORF clone (NM_005356.3) Inquiry
CDCR239287 Mouse Lck ORF Clone(NM_001162433.1) Inquiry
CDCR249407 Mouse Lck ORF Clone(NM_010693.3) Inquiry
CDCR372350 Rat Lck ORF Clone(NM_001100709.1) Inquiry
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