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Panoply™ Human LCK Knockdown Stable Cell Line

Cat.No.
CSC-DC008589
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
LCK
Synonyms
LSK; YT16; p56lck; pp58lck
Gene Description
lymphocyte-specific protein tyrosine kinase
Gene ID
UniProt ID
P06239
mRNA Refseq
Protein Refseq
Chromosome Location
1p34.3
Function
ATP binding; ATPase binding; CD4 receptor binding; CD8 receptor binding; SH2 domain binding; SH2 domain binding; glycoprotein binding; non-membrane spanning protein tyrosine kinase activity; phosphatidylinositol 3-kinase binding; protein C-terminus binding; protein binding; protein kinase binding; protein serine/threonine phosphatase activity; protein serine/threonine phosphatase activity; protein tyrosine kinase activity; protein tyrosine kinase activity; protein tyrosine kinase activity; protein tyrosine kinase activity;
Pathway
Adaptive Immune System, organism-specific biosystem; Alpha-synuclein signaling, organism-specific biosystem; Atypical NF-kappaB pathway, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; CD28 co-stimulation, organism-specific biosystem; CD28 dependent PI3K/Akt signaling, organism-specific biosystem; CD28 dependent Vav1 pathway, organism-specific biosystem;
MIM

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