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shRNA set against Human DYRK1A (NM_001396.3)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH282265

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Gene Information

Cat. No. SHH282265
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr DYRK1A
Gene Name DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A [ Homo sapiens ]
Gene Symbol DYRK1A
Synonyms MNB; DYRK; HP86; MNBH; MRD7; DYRK1
Gene Description dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
GeneID 1859
Uni ProtID Q13627
mRNA Refseq NM_101395.2
Protein Refseq NP_567824.1
Chromosome Location 21q22.13
Function ATP binding; non-membrane spanning protein tyrosine kinase activity; protein binding; protein kinase activity; protein self-association; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity; protein tyrosine kinase activity; tau protein binding;
Pathway Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; G0 and Early G1, organism-specific biosystem; Hedgehog Signaling Pathway, organism-specific biosystem; Mitotic G1-G1/S phases, organism-specific biosystem;
MIM 600855
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