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shRNA set against Human CCR5 (NM_000579.3)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH258181

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Gene Information

Cat. No. SHH258181
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr CCR5
Gene Name CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) [ Homo sapiens ]
Gene Symbol CCR5
Synonyms CKR5; CCR-5; CD195; CKR-5; CCCKR5; CMKBR5; IDDM22; CC-CKR-5
Gene Description chemokine (C-C motif) receptor 5
Gene ID 1234
Uni Prot ID P51681
m RNA Refseq NM_000579.3
Protein Refseq NP_000570.1
Chromosome Location 3p21.31
Function C-C chemokine binding; C-C chemokine receptor activity; C-C chemokine receptor activity; actin binding; chemokine (C-C motif) ligand 5 binding; chemokine receptor activity; coreceptor activity; phosphatidylinositol phospholipase C activity; protein binding;
Pathway Binding and entry of HIV virion, organism-specific biosystem; Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem;
MIM 601373
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