shRNA set against Human CASP3 (NM_004346.3)

Name: shRNA set against Human CASP3 (NM_004346.3)
SKU: SHH254973
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHH254973

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Product Information

Gene Information

Cat. No.	SHH254973
Description	The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr	CASP3
Gene Name	CASP3 caspase 3, apoptosis-related cysteine peptidase [ Homo sapiens ]
Species	Human
Report Gene	GFP
Storage	The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.

Gene Name	CASP3 caspase 3, apoptosis-related cysteine peptidase [ Homo sapiens ]
Gene Symbol	CASP3
Synonyms	CPP32; SCA-1; CPP32B
Gene Description	caspase 3, apoptosis-related cysteine peptidase
GeneID	836
Uni ProtID	P42574
mRNA Refseq	NM_032991.2
Protein Refseq	NP_116786.1
Chromosome Location	4q34
Function	aspartic-type endopeptidase activity; cyclin-dependent protein kinase inhibitor activity; cysteine-type endopeptidase activity; cysteine-type endopeptidase activity; peptidase activity; protein binding;
Pathway	Activation of DNA fragmentation factor, organism-specific biosystem; Activation of caspases through apoptosome-mediated cleavage, organism-specific biosystem; Alpha6-Beta4 Integrin Signaling Pathway, organism-specific biosystem; Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Alzheimers Disease, organism-specific biosystem; Amoebiasis, organism-specific biosystem;
MIM	600636

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