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shRNA set against Mouse CASP3 (NM_009810.2)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH254977

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Gene Information

Cat. No. SHH254977
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr CASP3
Gene Name Casp3 caspase 3 [ Mus musculus ]
Species Mouse
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name Casp3 caspase 3 [ Mus musculus ]
Gene Symbol Casp3
Synonyms CC3; AC-3; Lice; Yama; mldy; CPP32; Apopain; Caspase-3; A830040C14Rik
Gene Description caspase 3
GeneID 12367
Uni ProtID P70677
mRNA Refseq NM_009810.2
Protein Refseq NP_033940.1
Chromosome Location 8 B1.1; 8 26.0 cM
Function aspartic-type endopeptidase activity; cyclin-dependent protein kinase inhibitor activity; cysteine-type endopeptidase activity; cysteine-type endopeptidase activity; cysteine-type peptidase activity; cysteine-type peptidase activity; hydrolase activity; peptidase activity; peptidase activity; peptidase activity; peptidase activity; phospholipase A2 activator activity; protein binding;
Pathway Activation of DNA fragmentation factor, organism-specific biosystem; Activation of caspases through apoptosome-mediated cleavage, organism-specific biosystem; Alpha6-Beta4 Integrin Signaling Pathway, organism-specific biosystem; Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem;
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