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CASP3


Official Full Name
caspase 3
Organism
Homo sapiens
Gene ID
836
Background
The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. [provided by RefSeq, Aug 2017]
Synonyms
CPP32; SCA-1; CPP32B

Cat.No. Product Name Price
SHH254973 shRNA set against Human CASP3 (NM_004346.3) Inquiry
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SHG142377 shRNA set against Mouse Casp3(NM_009810.2) Inquiry
SHG142459 shRNA set against Rat Casp3(NM_012922.2) Inquiry
SHG142549 shRNA set against Human CASP3(NM_004346.3) Inquiry
SHW005233 shRNA set against Chicken CASP3 (NM_204725) Inquiry
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