shRNA set against Human BLM (NM_000057.2)

Name: shRNA set against Human BLM (NM_000057.2)
SKU: SHH246866
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHH246866

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Product Information

Gene Information

Cat. No.	SHH246866
Description	The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr	BLM
Gene Name	BLM Bloom syndrome, RecQ helicase-like [ Homo sapiens ]
Species	Human
Report Gene	GFP
Storage	The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.

Gene Name	BLM Bloom syndrome, RecQ helicase-like [ Homo sapiens ]
Gene Symbol	BLM
Synonyms	BS; RECQ2; RECQL2; RECQL3
Gene ID	641
Uni Prot ID	P54132
m RNA Refseq	NM_000057.2
Protein Refseq	NP_000048.1
Chromosome Location	15q26.1
Function	ATP binding; ATP-dependent 3-5 DNA helicase activity; ATP-dependent DNA helicase activity; ATP-dependent DNA helicase activity; ATP-dependent helicase activity; ATPase activity; G-quadruplex DNA binding; bubble DNA binding; four-way junction helicase activity; helicase activity; p53 binding; protein binding; single-stranded DNA binding;
Pathway	BRCA1-associated genome surveillance complex (BASC), organism-specific biosystem; Blooms syndrome complex, organism-specific biosystem; Fanconi anemia pathway, organism-specific biosystem; Fanconi anemia pathway, conserved biosystem; Homologous recombination, organism-specific biosystem; Homologous recombination, conserved biosystem; Integrated Breast Cancer Pathway, organism-specific biosystem;
MIM	604610

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