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Mouse Blm cDNA Clone(NM_001042527.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFG018534

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Product Information

Gene Information

Cat. No. CDFG018534
Product Type cDNA clone
Gene Abbr Blm
Species Mouse
ORF Size 4251bp
Size 10 ug
Vector pCMV6Entry
Target Gene BLM
Background The Bloom syndrome is an autosomal recessive disorder characterized by growth deficiency, microcephaly and immunodeficiency among others. It is caused by homozygous or compound heterozygous mutation in the gene encoding DNA helicase RecQ protein on chromosome 15q26. This Bloom-associated helicase unwinds a variety of DNA substrates including Holliday junction, and is involved in several pathways contributing to the maintenance of genome stability. Identification of pathogenic Bloom variants is required for heterozygote testing in at-risk families. [provided by RefSeq, May 2020]
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