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Human BLM Knockdown Cell Line-HeLa

Cat.No.
CSC-RK0025
Abbr
HeLa-HuBLM Knockdown
Alias
BLM,BS,RECQ2,RECQL3,RECQL2,MGC126616,MGC131618,MGC131620,
Growth Properties
Adherent
Host Cell
HeLa
Morphology
Epithelial
Shipping
Dry ice
Species
Human
Background
The Bloom syndrome gene product is related to the RecQ subset of DExH box-containing DNA helicases and has both DNA-stimulated ATPase and ATP-dependent DNA helicase activities. Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3"-5" helicase activity. The normal protein may act to suppress inappropriate recombination.

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