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shRNA set against Human ADAM17(NM_003183.4)

For research use only. Not intended for any clinical use.

Cat. No. :   SHG038189

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Gene Information

Cat. No. SHG038189
Description Each set contains 4 shRNA expression constructs. The hairpin consists of a 7 base loop and 19~29 base stem optimized for the specific gene sequence. The sequences of 19~29mer shRNAi will be delivered with shRNA clones.
Gene Abbr ADAM17
Gene Name ADAM17 ADAM metallopeptidase domain 17 [ Homo sapiens ]
Species Human
Report Gene eGFP
Content Each set contains 4 shRNA expression constructs. The hairpin consists of a 7 base loop and 19~29 base stem optimized for the specific gene sequence.
Promoter H1
Selection Puromycin
Format 5 μg purified plasmid
Unit Size 5 μg
Sequence The sequences of 19~29mer shRNAi will be delivered with shRNA clones.
Shipping Typically ships in 2-3 weeks
Gene Name ADAM17 ADAM metallopeptidase domain 17 [ Homo sapiens ]
Gene Symbol ADAM17
Synonyms CSVP; TACE; NISBD; ADAM18; CD156B
Gene Description ADAM metallopeptidase domain 17 (tumor necrosis factor, alpha, converting enzyme)
GeneID 6868
Uni ProtID B2RNB2
mRNA Refseq NM_003183.4
Protein Refseq NP_003174.3
Chromosome Location 2p25
Function PDZ domain binding; SH3 domain binding; integrin binding; interleukin-6 receptor binding; metalloendopeptidase activity; metalloendopeptidase activity; metalloendopeptidase activity; metallopeptidase activity; metallopeptidase activity; metallopeptidase activity; protein binding; zinc ion binding;
Pathway Activated NOTCH1 Transmits Signal to the Nucleus, organism-specific biosystem; Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Alzheimers Disease, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Delta-Notch Signaling Pathway, organism-specific biosystem; Disease, organism-specific biosystem;
MIM 603639
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