Transfected Stable Cell Lines
Reliable | High-Performance | Wide Rage
Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CLOE-1944 Host Cell : HEK293
| Cat. No. | CLOE-1944 |
| Description | This cell lysate overexpresses rat Adam17 (Met1-Asp563) with a C-terminal polyhistidine tag. Purification of target protein from this cell lysate has been verified. |
| Introduction | This cell lysate overexpresses rat Adam17 (Met1-Asp563) with a C-terminal polyhistidine tag. Purification of target protein from this cell lysate has been verified. |
| Target Gene | Adam17 |
| Host Cell | HEK293 |
| Host Cell Species | Homo sapiens (Human) |
| Applications | Positive control for Western Blot (WB), antibody verification, protein purification. |
| Growth Properties | Cells are cultured as a monolayer at 37°C in a humidified atmosphere with 5% CO2. Split at 80-90% confluence, approximately 1:3-1:6. |
| Media Type | Cells were cultured in DMEM supplemented with 10% fetal bovine serum. |
| Freeze Medium | Complete medium supplemented with 10% (v/v) DMSO |
| Storage | Upon receipt, store at 4℃ , or prepare aliquots and store at -80℃. Multiple freeze-thaw cycles should be avoided. |
| Shipping | Ice package |
| Gene Name | Adam17 a disintegrin and metallopeptidase domain 17 [ Mus musculus ] |
| Gene Symbol | Adam17 |
| Synonyms | Tace; CD156b |
| Gene Description | a disintegrin and metallopeptidase domain 17 |
| GeneID | 11491 |
| Uni ProtID | Q3UEW9 |
| mRNA Refseq | NM_009615.5 |
| Protein Refseq | NP_033745.4 |
| Chromosome Location | 12 A1.3; 12 3.0 cM |
| Function | PDZ domain binding; SH3 domain binding; hydrolase activity; integrin binding; interleukin-6 receptor binding; metal ion binding; metalloendopeptidase activity; metallopeptidase activity; metallopeptidase activity; peptidase activity; protein binding; zinc ion binding; |
| Pathway | Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Delta-Notch Signaling Pathway, organism-specific biosystem; Disease, organism-specific biosystem; Growth hormone receptor signaling, organism-specific biosystem; Immune System, organism-specific biosystem; |
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