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Human ADAM17 ORF clone (NM_003183.4)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR024436

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Gene Information

Cat. No. CDCR024436
Description Homo sapiens ADAM metallopeptidase domain 17 (ADAM17), mRNA.
Product Type ORF clone
Gene Abbr ADAM17
Gene Name ADAM17 ADAM metallopeptidase domain 17 [ Homo sapiens ]
Species Human
ORF Size 2475
Format purified plasmid or bacterial stock
Vector pDONR
Gene Name ADAM17 ADAM metallopeptidase domain 17 [ Homo sapiens ]
Gene Symbol ADAM17
Synonyms CSVP; TACE; NISBD; ADAM18; CD156B
Gene Description ADAM metallopeptidase domain 17 (tumor necrosis factor, alpha, converting enzyme)
GeneID 6868
Uni ProtID B2RNB2
mRNA Refseq NM_003183.4
Protein Refseq NP_003174.3
Chromosome Location 2p25
Function PDZ domain binding; SH3 domain binding; integrin binding; interleukin-6 receptor binding; metalloendopeptidase activity; metalloendopeptidase activity; metalloendopeptidase activity; metallopeptidase activity; metallopeptidase activity; metallopeptidase activity; protein binding; zinc ion binding;
Pathway Activated NOTCH1 Transmits Signal to the Nucleus, organism-specific biosystem; Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Alzheimers Disease, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Delta-Notch Signaling Pathway, organism-specific biosystem; Disease, organism-specific biosystem;
MIM 603639
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