Residual DNA Size Analysis Kit-Pichia Pastoris

Pichia pastoris, also known as Komagataella pastoris or Komagataella phaffii, is a methylotrophic yeast. This microorganism is widely used as a host organism for recombinant protein expression. Due to its ability to grow on methanol as a carbon source, Pichia pastoris can be induced to produce high yields of protein under controlled conditions, making it a very valuable tool in commercial biotechnology and research laboratories. As a eukaryotic organism, Pichia pastoris can undergo complex modifications such as glycosylation, disulfide bond formation, and protein folding, which are essential for the function of many eukaryotic proteins. This makes Pichia pastoris a preferred system for the production of therapeutic proteins, vaccines, and other biopharmaceuticals. However, a key consideration in the production process using genetically modified organisms (GMOs) such as Pichia pastoris is the presence of residual host cell DNA and possible contamination in the final protein product. Regulatory agencies around the world strictly limit the amount and size of residual host cell DNA in biopharmaceuticals to ensure safety and efficacy. When meeting these regulatory requirements, the Pichia pastoris-specific residual DNA size analysis kit becomes an indispensable tool. The kit is designed to help biopharmaceutical companies and research institutions quantify and analyze the size distribution of residual DNA in their biological products.