Recombinant Mouse TrkA (C-6His)

Name: Recombinant Mouse TrkA (C-6His)
SKU: RP00319
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00319 Tag : C-6His

Expressed Region : Ala34-Pro418 Expression System : Human Cell

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Product Information

Gene Information

Cat. No.	RP00319
Description	The Recombinant Mouse TrkA (C-6His) is produced in our Human Cell expression system. The amino acid region expressed is Ala34-Pro418 with a 6His tag at the C terminus.
Species	Mouse
Tag	C-6His
Mol Weight	42.9 KDa
Conjugate	Unconjugated
Format	Powder
Expressed Region	Ala34-Pro418
Expression System	Human Cell
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	Trka
Background	This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, cognitive disability and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.
Synonyms	NTRK1; NTRK-1; p140-TrkA; TRK1-transforming tyrosine kinase protein; TrkA; Trk-A; TRKAOncogene TRK; TRKTRK1

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