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Human TrkA ORF clone(NM_002529.3)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCL186627

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Product Information

Gene Information

Cat. No. CDCL186627
Product Type ORF clone
Gene Abbr TrkA
Species Human
ORF Size bp
Vector pMD18-T
Warning This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Storage store at -20°C
Target Gene TRKA
Background This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, cognitive disability and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq, Jul 2008]
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