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Human NTRK1(His/Fc) HEK293 Cell Lysate

For research use only. Not intended for any clinical use.

Cat. No. :   CLOE-1020 Host Cell :   HEK293

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Cell Lysate Information

Gene Information

Cat. No. CLOE-1020
Introduction This cell lysate over-expresses extracellular domain of human NTRK1 (NP_002520.2) (Met 1-Pro 382) fused with a polyhistidine tag and the Fc region of human IgG1 at the C-terminus.
Target Gene NTRK1
Host Cell HEK293
Host Cell Species Homo sapiens (Human)
Applications Positive control for Western Blot (WB), antibody verification, protein purification
Growth Properties Cells are cultured as a monolayer at 37°C in a humidified atmosphere with 5% CO2. Split at 80-90% confluence, approximately 1:3-1:6.
Media Type Cells were cultured in DMEM supplemented with 10% fetal bovine serum.
Freeze Medium Complete medium supplemented with 10% (v/v) DMSO
Storage Upon receipt, store at 4°C, or prepare aliquots and store at -80°C. Multiple freeze-thaw cycles should be avoided.
Shipping Ice package
Gene Name NTRK1 neurotrophic tyrosine kinase, receptor, type 1 [ Homo sapiens ]
Gene Symbol NTRK1
Synonyms MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA
Gene Description neurotrophic tyrosine kinase, receptor, type 1
Gene ID 4914
Uni Prot ID P04629
m RNA Refseq NM_001012331.1
Protein Refseq NP_001012331.1
Chromosome Location 1q21-q22
Function ATP binding; nerve growth factor binding; NOT nerve growth factor binding; nerve growth factor receptor activity; neurotrophin binding; protein binding; protein homodimerization activity; transmembrane receptor protein tyrosine kinase activity;
Pathway ARMS-mediated activation, organism-specific biosystem; Activation of TRKA receptors, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; Frs2-mediated activation, organism-specific biosystem;
MIM 191315
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