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shRNA set against Human NTRK1 (NM_002529.3)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH355780

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Gene Information

Cat. No. SHH355780
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr NTRK1
Gene Name NTRK1 neurotrophic tyrosine kinase, receptor, type 1 [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name NTRK1 neurotrophic tyrosine kinase, receptor, type 1 [ Homo sapiens ]
Gene Symbol NTRK1
Synonyms MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA
Gene Description neurotrophic tyrosine kinase, receptor, type 1
Gene ID 4914
Uni Prot ID P04629
m RNA Refseq NM_001012331.1
Protein Refseq NP_001012331.1
Chromosome Location 1q21-q22
Function ATP binding; nerve growth factor binding; NOT nerve growth factor binding; nerve growth factor receptor activity; neurotrophin binding; protein binding; protein homodimerization activity; transmembrane receptor protein tyrosine kinase activity;
Pathway ARMS-mediated activation, organism-specific biosystem; Activation of TRKA receptors, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; Frs2-mediated activation, organism-specific biosystem;
MIM 191315
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