Recombinant Mouse Tnfrsf4 (N-Fc)

Name: Recombinant Mouse Tnfrsf4 (N-Fc)
SKU: RP00533

Cat.No. : RP00533 Tag: N-Fc

Expressed Region: Val20-Pro211 Expression System: Human Cell

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Product Details

Target Information

Cat. No.	RP00533
Description	Recombinant Mouse Tnfrsf4 (N-Fc) is produced in our Human Cell expression system. The amino acid region expressed is Val20-Pro211 with a Fc tag at the N terminus.
Species	Mouse
Tag	N-Fc
Mol. Weight	47.4 KDa
Expressed Region	Val20-Pro211
Expression System	Human Cell
Format	Powder
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Conjugate	Unconjugated
Endotoxin Level	< 1 EU/µg of protein by LAL method
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	Tnfrsf4
Background	The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.
Synonyms	Tumor necrosis factor receptor superfamily member 4;Tnfrsf4;OX40;CD134;Txgp1

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