Biotinylated Human TNFRSF4 (C-Fc-Avi)

Name: Biotinylated Human TNFRSF4 (C-Fc-Avi)
SKU: RP00500
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00500 Tag : C-Fc-Avi

Expressed Region : Leu29-Ala216 Expression System : Human Cell

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Product Information

Gene Information

Cat. No.	RP00500
Description	Biotinylated Human TNFRSF4 (C-Fc-Avi) is produced in our Human Cell expression system. The amino acid region expressed is Leu29-Ala216 with a Fc-Avi tag at the C terminus.
Species	Human
Tag	C-Fc-Avi
Mol Weight	48.6 KDa
Conjugate	Biotinylated
Format	Powder
Expressed Region	Leu29-Ala216
Expression System	Human Cell
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	TNFRSF4
Background	The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.
Synonyms	Tumor necrosis factor receptor superfamily member 4; ACT35 antigen; OX40L receptor; TAX transcriptionally-activated glycoprotein 1 receptor; CD134; TNFRSF4; TXGP1L

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