Recombinant Mouse SOST (C-6His)

Name: Recombinant Mouse SOST (C-6His)
SKU: RP00179
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00179 Tag : C-6His

Expressed Region : Gln24-Tyr211 Expression System : Human Cell

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Product Information

Gene Information

Cat. No.	RP00179
Description	The Recombinant Mouse SOST (C-6His) is produced in our Human Cell expression system. The amino acid region expressed is Gln24-Tyr211 with a 6His tag at the C terminus.
Species	Mouse
Tag	C-6His
Mol Weight	21.9 KDa
Conjugate	Unconjugated
Format	Powder
Expressed Region	Gln24-Tyr211
Expression System	Human Cell
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	Sost
Background	Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease.
Synonyms	Sclerostin; Sost

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